The influence of simulated light scattering on automated perimetric threshold measurements
D. K. Heuer, D. R. Anderson, R. W. Knighton, W. J. Feuer and M. G. Gressel
Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles.
The effect of light scattering by ocular media opacities on OCTOPUS and
Humphrey perimeter threshold measurements was simulated with randomly
ordered sequences of six ground-glass diffusers in the right eyes of five
subjects. Threshold measurements were performed at 0 degrees, 5 degrees, 10
degrees, 15 degrees, 20 degrees, and 25 degrees nasally along the 180
degrees meridian with the F4 program on an OCTOPUS perimeter, and with
twice-repeated profiles on a Humphrey perimeter. The reduction in
differential light sensitivity correlated well with the 2.7-dB to 16.7-dB
reduction in stimulus intensity caused by the 46% to 98% scattering of
incident light by the diffusers. Contrast sensitivity in the presence of a
glare source (Miller-Nadler glare test) was also affected by the diffusers,
such that a 75% contrast target was not visible through the strongest
diffuser whereas a 5% contrast target was visible without a diffuser.
Conversely, the diffusers had very little effect on visual acuity
measurements that were performed with projected high-contrast targets in a
darkened room. Our data suggest that even minimal light scattering, such as
might be caused by a cataract that has a relatively insignificant effect on
visual acuity, may influence threshold measurements.
