Hemoglobin spherulosis in the vitreous cavity
H. E. Grossniklaus, K. E. Frank, D. C. Farhi, G. Jacobs and W. R. Green
Department of Pathology, University Hospital of Cleveland, Case Western Reserve University, OH.
A 50-year-old woman was evaluated for a subretinal hemorrhage that extended
into the vitreous of the right eye. Examination showed multiple refractile
brown spherules in the vitreous. A vitrectomy was performed, and pathologic
examination of the spherules showed them to be composed of free hemoglobin.
Free-hemoglobin spherulosis in the vitreous, like cholesterosis bulbi, is a
manifestation of vitreous hemorrhage.
