Monozygotic twins with age-related macular degeneration

S. M. Meyers and A. A. Zachary
Department of Ophthalmology, Cleveland Clinic Foundation, OH 44106.

This clinical study, to the best of our knowledge, is the first report of severe age-related macular degeneration in both identical twins, documented as monozygotic by genetic testing. This suggests that genetic factors may be of primary importance in certain cases of age-related macular degeneration.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Age-Related Macular Degeneration
de Jong
NEJM 2006;355:1474-1485.
FULL TEXT  

Association of HLA Class I and Class II Polymorphisms with Age-Related Macular Degeneration
Goverdhan et al.
IOVS 2005;46:1726-1734.
ABSTRACT | FULL TEXT  

The genetics of inherited macular dystrophies
Michaelides et al.
J. Med. Genet. 2003;40:641-650.
ABSTRACT | FULL TEXT  

An Autosomal Dominant Bull's-Eye Macular Dystrophy (MCDR2) that Maps to the Short Arm of Chromosome 4
Michaelides et al.
IOVS 2003;44:1657-1662.
ABSTRACT | FULL TEXT  

From the Cover: Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
Crabb et al.
Proc. Natl. Acad. Sci. USA 2002;99:14682-14687.
ABSTRACT | FULL TEXT  

Symmetry of Bilateral Lesions in Geographic Atrophy in Patients With Age-Related Macular Degeneration
Bellmann et al.
Arch Ophthalmol 2002;120:579-584.
ABSTRACT | FULL TEXT  

Central areolar choroidal dystrophy associated with dominantly inherited drusen
Klevering et al.
Br. J. Ophthalmol. 2002;86:91-96.
ABSTRACT | FULL TEXT  

Macular Pigment and Risk for Age-Related Macular Degeneration in Subjects from a Northern European Population
Beatty et al.
IOVS 2001;42:439-446.
ABSTRACT | FULL TEXT  

ABCR Gene Analysis in Familial Exudative Age-Related Macular Degeneration
Souied et al.
IOVS 2000;41:244-247.
ABSTRACT | FULL TEXT