Latent disseminated blastomycosis with choroidal involvement
H. Lewis, T. M. Aaberg, D. R. Fary and T. S. Stevens
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee.
A 36-year-old man developed blurred vision and a cough five months after
traveling to an area from where a large outbreak of acute blastomycosis had
been reported. Examination revealed a left choroidal lesion in the macular
region, skin lesions on the right calf, and a left lung apical infiltrate.
Histopathologic examination of the skin lesion demonstrated a granulomatous
inflammation and broad based, budding yeast characteristic of Blastomyces
dermatitidis. Amphotericin B therapy produced a rapid resolution of both
choroidal and pulmonary lesions. During a six-month follow-up, there was no
evidence of recurrence.
