Multiple myeloma involving the iris
E. P. Shakin, J. J. Augsburger, R. C. Eagle Jr, H. Ehya, J. A. Shields, D. Fischer and D. G. Koepsell
Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107.
Intraocular invasion by neoplastic plasma cells is a rare ophthalmic
manifestation of plasma cell dyscrasias. A 67-year-old man who had
documented multiple myeloma presented with an infiltration of the iris that
simulated a nongranulomatous uveitis. Cytologic examination of the aspirate
obtained by anterior chamber paracentesis demonstrated that the infiltrate
was composed of neoplastic plasma cells.