Malignant glioma of the optic chiasm eight years after radiotherapy for prolactinoma

T. J. Hufnagel, J. H. Kim, R. Lesser, J. M. Miller, J. J. Abrahams, J. Piepmeier and E. E. Manuelidis
Section of Neuropathology, Yale University School of Medicine, New Haven, Conn 06510.

A 41-year-old man had rapidly progressive visual loss caused by a malignant glioma that developed in the optic chiasm eight years after radiation therapy for a recurrent prolactinoma. Radiation-induced glioma should be considered as a cause of progressive visual loss in patients who have received irradiation in the region of the sella turcica.