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Malignant Glioma of the Optic Chiasm Eight Years After Radiotherapy for Prolactinoma
Thierry J. Hufnagel, MD;
Jung H. Kim, MD;
Robert Lesser, MD;
Joseph M. Miller, MD;
James J. Abrahams, MD;
Joseph Piepmeier, MD;
Elias E. Manuelidis, MD
Arch Ophthalmol. 1988;106(12):1701-1705.
Abstract
• A 41-year-old man had rapidly progressive visual loss caused by a malignant glioma that developed in the optic chiasm eight years after radiation therapy for a recurrent prolactinoma. Radiation-induced glioma should be considered as a cause of progressive visual loss in patients who have received irradiation in the region of the sella turcica.
Author Affiliations
From the Sections of Neuropathology (Drs Hufnagel, Kim, and Manuelidis) and Neurosurgery (Dr Piepmeier), Department of Surgery; Section of Neuroradiology, Department of Diagnostic Imaging (Dr Abrahams); and the Department of Ophthalmology and Visual Science (Drs Hufnagel, Lesser, and Miller), Yale University School of Medicine, New Haven, Conn.
Footnotes
Accepted for publication March 19, 1988.
Reprint requests to Section of Neuropathology, Yale University School of Medicine, 333 Cedar St, PO Box 3333, New Haven, CT 06510 (Dr Hufnagel).
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