 |
|
Retinal Pigment Epithelial Cells in Culture Produce Retinal Vascular Mitogens
Hong Chai Wong, FRCS;
Mike Boulton, PhD;
David McLeod, FRCS;
Meryl Bayly;
Peter Clark, MSc;
John Marshall, PhD
Arch Ophthalmol. 1988;106(10):1439-1443.
Abstract
• Conditioned medium from human retinal pigment epithelial cells in culture significantly stimulated the proliferation of subcultured bovine retinal capillary endothelial cells, pericytes, and freshly isolated retinal microvessels. The vascular mitogenic activity enhanced that of retinal crude extract. No evidence emerged of an inhibitor of microvascular cellular proliferation produced by retinal pigment epithelial cells.
Author Affiliations
From the Surgical Vitreoretinal Unit, Moorfields Eye Hospital (Drs Wong and McLeod), and the Department of Clinical Ophthalmology, Institute of Ophthalmology (Drs Boulton and Marshall, Ms Bayly, and Mr Clark), London.
Footnotes
Accepted for publication June 16, 1988.
Reprint requests to Institute of Ophthalmology, Judd Street, London WCIH 9QS, United Kingdom (Dr Boulton).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
A Novel Serum-Free Method for Culturing Human Prenatal Retinal Pigment Epithelial Cells
Gamm et al.
IOVS 2008;49:788-799.
ABSTRACT
| FULL TEXT
Vessel Formation by Choroidal Endothelial Cells In Vitro Is Modulated by Retinal Pigment Epithelial Cells
Sakamoto et al.
Arch Ophthalmol 1995;113:512-520.
ABSTRACT
Human retinal pigment epithelial cells from different donors continuously produce a vascular endothelial cell-stimulating factor into serum-free medium
Yang et al.
J. Cell Sci. 1993;104:211-218.
ABSTRACT
Bovine Retinal Pigment Epithelium Promotes Proliferation of Choroidal Endothelium In Vitro
Morse et al.
Arch Ophthalmol 1989;107:1659-1663.
ABSTRACT
|
