Intravenous administration of clonidine reduces intraocular pressure and alters ocular blood flow
Weigert et al.
Br J Ophthalmol 2007;91:1354-1358.
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The sensitivity and specificity of 0.5% apraclonidine in the diagnosis of oculosympathetic paresis
Koc et al.
Br J Ophthalmol 2005;89:1442-1444.
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Apraclonidine Attenuates the Increases in Spinal Excitatory Amino Acid Release in Rats with Adjuvant-Induced Inflammation
Lin et al.
Anesth. Analg. 2002;94:701-705.
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Effectiveness of apraclonidine 1% in preventing intraocular pressure rise following macular hole surgery
Sciscio and Casswell
Br J Ophthalmol 2001;85:164-168.
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Ocular Effects of Apraclonidine in Horner Syndrome
Morales et al.
Arch Ophthalmol 2000;118:951-954.
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Effect of Brimonidine Tartrate on Ocular Hemodynamic Measurements
Lachkar et al.
Arch Ophthalmol 1998;116:1591-1594.
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Medical Management of Glaucoma
Alward
NEJM 1998;339:1298-1307.
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Effects of 0.5% apraclonidine on optic nerve head and peripapillary retinal blood flow
Kim and Kim
Br J Ophthalmol 1997;81:1070-1072.
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A 90-Day Study of the Efficacy and Side Effects of 0.25% and 0.5% Apraclonidine vs 0.5% Timolol
Stewart et al.
Arch Ophthalmol 1996;114:938-942.
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Questions Concerning the Role of Apraclonidine in the Management of Glaucoma
Robin
Arch Ophthalmol 1995;113:712-714.
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The Efficacy of Apraclonidine as an Adjunct to Timolol Therapy
Stewart et al.
Arch Ophthalmol 1995;113:287-292.
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Clinical Experience With the Long-term Use of 1% Apraclonidine: Incidence of Allergic Reactions
Butler et al.
Arch Ophthalmol 1995;113:293-296.
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Selective {alpha}2-Adrenerigc Agonists B-HT 920 and UK14304-18: Effects on Aqueous Humor Dynamics in Monkeys
Serle et al.
Arch Ophthalmol 1991;109:1158-1162.
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Effects of Topical Flurbiprofen on the Intraocular Pressure Lowering Effects of Apraclonidine and Timolol
Sulewski et al.
Arch Ophthalmol 1991;109:807-809.
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Cardiovascular and Intraocular Pressure Effects and Plasma Concentrations of Apraclonidine
Coleman et al.
Arch Ophthalmol 1990;108:1264-1267.
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The Effects of Apraclonidine on Conjunctival Oxygen Tension
Serdahl et al.
Arch Ophthalmol 1989;107:1777-1779.
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Apraclonidine Hydrochloride in Vitreoretinal Surgery
Pulido et al.
Arch Ophthalmol 1989;107:316-317.
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Apraclonidine: A One-Week Dose-Response Study
Jampel et al.
Arch Ophthalmol 1988;106:1069-1073.
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Short-term Effects of Unilateral 1% Apraclonidine Therapy
Robin
Arch Ophthalmol 1988;106:912-915.
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Prevention of the Rise in Intraocular Pressure Following Neodymium-YAG Posterior Capsulotomy Using Topical 1% Apraclonidine
Pollack et al.
Arch Ophthalmol 1988;106:754-757.
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Effects of Topical ALO 2145 (p-Aminoclonidine Hydrochloride, Aplonidine Hydrochloride) on the Acute Intraocular Pressure Rise After Argon Laser Iridotomy-Reply
Robin et al.
Arch Ophthalmol 1988;106:308-309.
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Effects of Topical ALO 2145 (p-Aminoclonidine Hydrochloride, Aplonidine Hydrochloride) on the Acute Intraocular Pressure Rise After Argon Laser Iridotomy
Fourman
Arch Ophthalmol 1988;106:307-308.
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Effects of Topical ALO 2145 (p-Aminoclonidine Hydrochloride) on the Acute Intraocular Pressure Rise After Argon Laser Iridotomy
Robin et al.
Arch Ophthalmol 1987;105:1208-1211.
ABSTRACT
2-agonist) in 21 normal volunteers for one month. Criteria measured included intraocular pressure (IOP), basal tear secretion, pupillary size, corneal sensitivity, heart rate, and blood pressure; urinalysis and blood chemistry studies were also performed. The mean (± SD) IOP fell 38.7%, from 17.5 ± 3.9 mm Hg to 10.7 ± 3.4 mm Hg, in five hours. The mean IOP remained between 23% and 30% below the pretreatment level when checked 12 hours after the last drop's instillation from day 8 through day 28 of the study. No clinically significant changes in mean systolic blood pressure, blood chemistry values, urinalysis results, basal tear secretion, or corneal sensitivity were noted. The mean heart rate and diastolic blood pressure were each significantly decreased at only one of nine time intervals. Dry mouth was noted at some time in 52% of volunteers. ALO 2145 seems to be effective in lowering IOP in normal volunteers, without marked cardiovascular effects.