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Robert B. Chambers, DO; Frederick H. Davidorf, MD; Jeffrey F. McAdoo; Donald W. Chakeres, MD

Arch Ophthalmol. 1987;105(7):917-921.

Abstract
• A series of 31 patients who presented with uveal mass lesions was studied with magnetic resonance imaging (MRI). Uveal melanoma was the presumed clinical diagnosis in 23 of the cases. Ten (43%) of these suspected melanomas provided useful images on both spin-lattice (T₁)- and spin-spin (T₂)-weighted studies and these had characteristic features. The features include a high-intensity image on T₁-weighted studies with progressively decreasing relative intensity on T₂-weighted images. These findings are consistent with short T₁ and T₂ relaxation times. In contrast, three cases of carcinoma metastatic to the choroid demonstrated a relatively high signal intensity on both T₁- and T₂-weighted images. The short relaxation times exhibited by uveal melanomas are in contrast with the relatively long T₁ and T₂ times found in other malignant neoplasms. These characteristics may provide a noninvasive method for differentiation of malignant melanoma from other mass lesions within the uveal tract.

Author Affiliations
From the Departments of Ophthamology (Drs Chambers and Davidorf and Mr McAdoo) and Radiology (Dr Chakeres), The Ohio State University, Columbus.

Footnotes
Accepted for publication March 12, 1987.

Reprint requests to 456 W Tenth Ave, Columbus, OH 43210 (Dr Chambers).

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