Papillopathy caused by amiodarone
J. W. Gittinger Jr and G. K. Asdourian
Disc swelling and hemorrhages appeared in three eyes of two men receiving
amiodarone hydrochloride for cardiac arrhythmias. The initial diagnosis was
ischemic optic neuropathy, but visual acuity was preserved, and visual
field changes were present in only one eye. Amiodarone is a cationic
amphiphilic compound, and other drugs with this property have keratopathy,
retinopathy, and optic neuropathy as side effects. We believe our patients
had an amiodarone-induced papillopathy.