Orbital optic glioma in neurofibromatosis. Magnetic resonance diagnosis of perineural arachnoidal gliomatosis
S. R. Seiff, M. C. Brodsky, G. MacDonald, B. O. Berg, E. L. Howes Jr and W. F. Hoyt
Ophthalmic Plastic and Reconstructive Surgery Service, University of California Medical Center, San Francisco 94143.
In a patient with neurofibromatosis and orbital optic glioma, T2-weighted
axial magnetic resonance images showed a fusiform area of high signal
intensity with a central linear core of lower signal intensity. Computed
tomographic images did not show a corresponding variation in tumor density.
Histopathologic examination of the tumor revealed dense, circumferential,
perineural glial proliferation. This "arachnoidal gliomatosis" is a feature
of orbital optic gliomas in neurofibromatosis and, in our magnetic
resonance scans, accurately corresponded with the region of high signal
intensity within the tumor.
