Drug-induced pemphigoid. A spectrum of diseases
P. M. Fiore, I. H. Jacobs and D. B. Goldberg
Department of Ophthalmology, Eye Institute of New Jersey, Newark.
Drug-induced ocular pemphigoid has been reported to occur after long-term
use of topical glaucoma medications. We have reviewed the literature on
drug-induced ocular pemphigoid and have added our experience with five
patients with glaucoma who developed ocular cicatricial (benign mucosal)
pemphigoid after treatment with various topical glaucoma medications. We
also describe a case of timolol-induced ocular pemphigoid. The presentation
and progression of drug-induced ocular cicatricial pemphigoid can be
variable. We propose that drug-induced ocular pemphigoid represents a
spectrum of diseases ranging from a self-limiting, toxic form to a
progressive, immunologic form.
Drug-induced cicatrising granulomatous conjunctivitis
Kahana et al.
Br. J. Ophthalmol. 2007;91:691-692.
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A New Method for Measuring Progression in Patients With Ocular Cicatricial Pemphigoid
Rowsey et al.
Arch Ophthalmol 2004;122:179-184.
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Prevalence of ocular symptoms and signs with preserved and preservative free glaucoma medication
Pisella et al.
Br. J. Ophthalmol. 2002;86:418-423.
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The First International Consensus on Mucous Membrane Pemphigoid: Definition, Diagnostic Criteria, Pathogenic Factors, Medical Treatment, and Prognostic Indicators
Chan et al.
Arch Dermatol 2002;138:370-379.
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Enhanced Disruption of the Blood-Aqueous Barrier and the Incidence of Angiographic Cystoid Macular Edema by Topical Timolol and Its Preservative in Early Postoperative Pseudophakia
Miyake et al.
Arch Ophthalmol 2001;119:387-394.
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Incidence of ocular side effects of topical beta blockers in the Netherlands
van Beek et al.
Br. J. Ophthalmol. 2000;84:856-859.
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Therapeutic Drug Monitoring and the Eye
Lesar et al.
Journal of Pharmacy Practice 1989;2:357-374.
