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Scott R. Lambert, MD; Creig S. Hoyt, MD; James E. Jan, MD; James Barkovich, MD; Olof Flodmark, MD, PhD

Arch Ophthalmol. 1987;105(10):1371-1377.

Abstract
• We reviewed the clinical courses and computed tomographic (CT) and magnetic resonance imaging (MRI) scans of 30 infants and children with cortical blindness following hypoxic insults. The degree of injury to the striate and parastriate cortices and the area of the optic radiations were graded from 0 to 4 by a neuroradiologist. Only two children had normal scans of the posterior visual pathway and both had favorable visual outcomes. The visual recovery differed significantly with respect to the age at which the hypoxic insult occurred and CT and MRI abnormalities in the area of the optic radiations, but not with abnormalities in the striate or parastriate cortices. Our results suggest that CT and MRI scanning are helpful in prognosticating the visual potential of children with hypoxic cortical blindness.

Author Affiliations
From the Departments of Ophthalmology (Drs Lambert and Hoyt) and Radiology (Dr Barkovich), University of California, San Francisco; and the Division of Child Neurology (Dr Jan) and Department of Neurology (Dr Flodmark), University of British Columbia, Vancouver, Canada.

Footnotes
Accepted for publication May 11, 1987.

Reprint requests to Department of Ophthalmology, University of California, San Francisco, Room A704, 400 Parnassus Ave, San Francisco, CA 94143 (Dr Hoyt).

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