Psammomatoid ossifying fibroma
C. E. Margo, A. Weiss and M. B. Habal
Fibro-osseous lesions represent a variety of bone proliferations each
characterized by different morphologic patterns of osteoid production.
Psammomatoid ossifying fibroma (POF) is characterized histologically by
numerous small round ossicles resembling psammoma bodies and is a locally
invasive lesion of facial and cranial bones. Two cases of POF arising in
the ethmoid sinus and involving the orbit are presented to emphasize the
importance of complete surgical removal of involved bones. Histologically,
portions of POF may demonstrate other patterns of osteoid production, which
resemble fibrous dysplasia and Paget's disease of bone. The variation in
radiodensity in POF on computed tomography is a function of the density of
psammomatoid ossicles and of the coexistence of other "minor" forms of bone
proliferation.
