Subfoveal choroidal neovascular membranes in age-related macular degeneration. Visual prognosis in eyes with relatively good initial visual acuity
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We determined the visual prognosis of 94 eyes in 92 patients having
age-related macular degeneration, a discrete choroidal neovascular membrane
directly under the center of the foveal avascular zone (subfoveal), and an
initial visual acuity of 20/100 or better. Of the patients who were
reexamined 24 months following their initial presentation, 77% had lost at
least four lines of vision and 64% had lost at least six lines. Estimation
of visual loss using a conservative assessment procedure showed four-line
visual loss in 65% of the patients and six-line loss in 50%. In general,
the better the visual acuity at the initial examination, the more likely
the patient was to have a smaller choroidal neovascular membrane. These
results suggest that it may be reasonable to consider a randomized clinical
trial of laser photocoagulation for this group of patients with a
relatively poor visual prognosis.
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