Visual acuity results following treatment of persistent hyperplastic primary vitreous
D. J. Karr and W. E. Scott
The visual acuity outcome of patients with persistent hyperplastic primary
vitreous (PHPV) was reviewed. A total of 48 patients with the diagnosis of
PHPV were seen at the University of Iowa, Iowa City, from 1971 through
1984. Twenty-five patients were managed nonsurgically, of which 23 had a
poor visual acuity outcome (less than or equal to 5/200). Two with mild
cases had visual acuities of 20/100 and 20/30. Twenty-three patients were
treated surgically. Five of these had no further postoperative
rehabilitation. Eighteen patients underwent surgery and aggressive optical
and occlusion therapy. Eight of these 18 patients (44%) had postoperative
visual acuities of 20/200 or better. These eight patients represent 17% of
the study population. Therefore, lensectomy-membranectomy procedures for
the purpose of effecting visual development are reasonable therapeutic
options in patients with PHPV in whom the findings are primarily anterior
in nature, surgery is performed at an early age, and aggressive amblyopia
therapy is instituted.
