Macular infarction after endophthalmitis treated with vitrectomy and intravitreal gentamicin
B. P. Conway and P. A. Campochiaro
We encountered two cases of macular infarction that occurred after
vitrectomy performed for mild endophthalmitis, which, on culture, yielded
Staphylococcus epidermidis. At the end of each vitrectomy, 0.4 mg of
gentamicin, 1.0 mg of cefazolin, and 0.32 mg of dexamethasone were injected
into the vitreous cavity. We are concerned that the macular lesion was a
retinal toxic effect of gentamicin because of the recent description of
similar lesions occurring after the inadvertent intraocular injection of
massive doses of this drug.
