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Gilles Chaine, MD; Philippe Attali, MD; Alain Gaudric, MD; Marie C. Colin, MD; Gabriel Quentel, MD; Gabriel Coscas, MD

Arch Ophthalmol. 1986;104(11):1632-1635.

Abstract
• Ocular fluorophotometry was performed in 24 patients with hypertension due to toxemia of pregnancy and in ten normal subjects. Patients showing features of accelerated hypertension in the fundus (eg, hemorrhage, cotton-wool spots, and disc edema) were excluded from the study. Fluorescein concentrations in the aqueous and posterior vitreous increased significantly in toxemic patients compared with those in normal subjects; the blood-aqueous barrier was disrupted earlier than the blood-retinal barrier. Nevertheless, these barriers were only disrupted when the arterial diameter was altered. Ocular fluorometric abnormalities disappeared after delivery in all but two cases.

Author Affiliations
From the Clinique Ophtalmologique Universitaire de Créteil (Drs Chaine, Attali, Gaudric, Quentel, and Coscas) and the Clinique Obstétricale de Créteil (Dr Colin), Créteil, France. Dr Chaine is now with Hôpital Avicenne, Bobigny, France.

Footnotes
Accepted for publication May 5, 1986.

Reprint requests to Service d'Ophtalmologie, Hôpital Avicenne, 125 route de Stalingrad, 93009 Bobigny, France (Dr Chaine).

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