Intravitreal amikacin in the treatment of bacterial endophthalmitis
J. H. Talamo, D. J. D'Amico and K. R. Kenyon
Intravitreal administration of broad-spectrum antibiotics is a widely
accepted component of initial therapy for bacterial endophthalmitis. Four
cases of culture-proved bacterial endophthalmitis are reported to
demonstrate the safety of intravitreal administration of amikacin sulfate
in conjunction with cephalosporins in patients. The benefits of using
amikacin rather than gentamicin sulfate in intravitreal drug therapy are
discussed, and a wider role for amikacin as the aminoglycoside of choice
for initial intravitreal injection in presumed bacterial endophthalmitis is
suggested.
