Intravenous pyogenic granuloma of the ocular adnexa. Report of two cases and review of the literature
L. Truong and R. L. Font
Intravenous pyogenic granuloma is a recently described form of pyogenic
granuloma (PG) in which the angiomatous proliferation is confined entirely
within the lumen of a vein. To our knowledge, only four cases involving the
ocular adnexa, including two that we encountered, have been described.
Histologically, this benign lesion is similar to PG of other locations and
is characterized by lobular congeries of capillaries embedded in a
fibromyxoid matrix containing scattered chronic inflammatory cells. The
whole lesion appears as a single polypoid mass projecting into the lumen of
a dilated vein. The histogenesis of this lesion remains obscure. Complete
local excision is the treatment of choice. Intravenous PG can be
differentiated from other intravascular fibroangiomatous proliferations,
including intravascular papillary endothelial hyperplasia, intravenous
atypical vascular proliferation, intravascular fasciitis, and organized
thrombus.
