Corneal endothelial morphology after anterior chamber lens implantation
D. B. Glasser, M. Matsuda, W. E. Gager and H. F. Edelhauser
The morphologic features of the corneal endothelium were investigated by
means of regional wide-field specular microscopy and computer-assisted
morphometry in 13 eyes of nine patients who had undergone intracapsular
cataract extraction with anterior chamber lens implantation more than one
year previously. The endothelial cells in these patients demonstrated a
significant increase in cellular elongation and the coefficient of
variation in mean cell area and a significant decrease in the percentage of
hexagonal endothelial cells when compared with age-matched controls (ten
eyes of ten patients). The clinical implications of these long-term
morphologic changes are unknown, but the changes may be indicative of an
unstable endothelium or may be an early sign of continuing cell loss.