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Claudia U. Richter, MD; George Arzeno, MD; Harry R. Pappas, MD; Claudia A. Arrigg, MD; Paul Wasson, MD; Roger F. Steinert, MD

Arch Ophthalmol. 1985;103(7):912-915.

Abstract
• Thirty-two eyes of 32 patients were treated with 0.5% timolol, 2% pilocarpine, or normal saline five and 30 minutes following neodymium-YAG laser posterior capsulotomy in a randomized, double-masked study. Mean maximum intraocular pressure (IOP) elevation was 8 2 mm Hg following treatment with normal saline, 5 3 mm Hg following treatment with 2% pilocarpine, and 1 ± 2 mm Hg following treatment with 0.5% timolol. Fewer patients treated with 0.5% timolol developed an IOP elevation of 5 mm Hg or more than control patients. One aphakic patient treated with 0.5% timolol developed a maximum IOP greater than or equal to 40 mm Hg. We found that treatment with 0.5% timolol after neodymium-YAG laser posterior capsulotomy provides partial protection from IOP elevation.

Author Affiliations
From the Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary, and the Department of Ophthalmology, Harvard Medical School, Boston.

Footnotes
Accepted for publication May 16, 1985.

Reprint requests to 50 Staniford St, Boston, MA 02114 (Dr Richter).

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