The histopathology of familial exudative vitreoretinopathy. A report of two cases
E. E. Boldrey, P. Egbert, J. D. Gass and T. Friberg
Two eyes were enucleated for angle-closure associated with familial
exudative vitreoretinopathy. Characteristic features included total retinal
detachment, peripheral retinal vascular proliferation, and a fibrovascular
preretinal membrane. Angle-closure glaucoma developed in one case when
sudden massive subretinal hemorrhage, associated with abnormal intraretinal
vessels, produced anterior displacement of the lens-iris diaphragm; in the
second case, angle-closure was associated with the development of rubeosis
iridis. Intraretinal inflammatory cells and exudates were also seen in the
enucleated eyes.
