Oversized donor grafts in penetrating keratoplasty. A randomized trial
D. G. Heidemann, A. Sugar, R. F. Meyer and D. C. Musch
One hundred seventy-three aphakic or phakic corneal transplants were
analyzed in a prospective randomized study to determine the effect of
oversized corneal donor buttons on intraocular pressure, corneal curvature
and astigmatism, wound dehiscence, and anterior chamber depth. We compared
93 oversized grafts with 80 same-sized grafts. In aphakic eyes, oversized
grafts showed a trend toward lower incidence of elevated intraocular
pressure during the early post-operative period and lower prevalence of
glaucoma at the final visit, although this was not statistically
significant. No such trends were seen in phakic eyes. Postoperative corneal
curvature was significantly steeper in oversized than same-sized grafts, in
both phakic and aphakic eyes; there was no difference in postoperative
astigmatism. Anterior chamber depth was significantly greater in oversized
grafts. Of four wound dehiscences, all occurred in same-sized grafts.
