This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (58)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

George H. Bresnick, MD; Randall Condit, MD; Stephen Syrjala; Mari Palta, PhD; Abigail Groo; Kathryn Korth

Arch Ophthalmol. 1984;102(9):1286-1293.

Abstract
• The dimensions of the foveal avascular zone (FAZ) were measured in fluorescein angiograms from 36 diabetic patients and 20 nondiabetic controls. The median values for longest diameter, mean diameter, and circumference were significantly greater in the diabetic group than in the control group. Longest diameters greater than 1.0 mm were found almost exclusively in eyes with proliferative diabetic retinopathy. The FAZ dimensions were strongly positively correlated with the severity of capillary nonperfusion in the posterior retina, but not with fluorescein leakage. The presence of proliferative diabetic retinopathy was also strongly correlated with capillary nonperfusion. Retinal capillary occlusion as the cause of FAZ enlargement in diabetic retinopathy is supported by these findings.

Author Affiliations
From the Department of Ophthalmology, University of Wisconsin Medical School, Madison.

Footnotes
Accepted for publication April 12, 1984.

Reprint requests to Department of Ophthalmology, University of Wisconsin, 600 Highland Ave, Madison, WI 53792 (Dr Bresnick).

This study was supported in part by grant EY-03084 from the National Eye Institute, National Institutes of Health, Bethesda, Md.

The fundus photographs were graded at the University of Wisconsin Fundus Photo Reading Center, Madison.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

An Electrophysiological Study of Retinal Function in the Diabetic Female Rat
Ramsey et al.
IOVS 2006;47:5116-5124.
ABSTRACT | FULL TEXT  

A randomised controlled feasibility trial of vitrectomy versus laser for diabetic macular oedema
Thomas et al.
Br J Ophthalmol 2005;89:81-86.
ABSTRACT | FULL TEXT  

Can a cilio-retinal artery influence diabetic maculopathy?
Knudsen and Lervang
Br J Ophthalmol 2002;86:1252-1255.
ABSTRACT | FULL TEXT  

Macular circulation in patients with diabetes mellitus with and without arterial hypertension
Arend et al.
Br J Ophthalmol 2000;84:1392-1396.
ABSTRACT | FULL TEXT  

Short-Wavelength Automated Perimetry and Capillary Density in Early Diabetic Maculopathy
Remky et al.
IOVS 2000;41:274-281.
ABSTRACT | FULL TEXT  

Diabetic tractional papillopathy: a new (and true) nosological entity?
McLEOD
Br J Ophthalmol 1999;83:257-258.
FULL TEXT  

Capillary Nonperfusion of the Retina in Diabetes Mellitus
Greven et al.
Arch Ophthalmol 1998;116:1260-1261.
FULL TEXT  

The Relationship of Macular Microcirculation to Visual Acuity in Diabetic Patients
Arend et al.
Arch Ophthalmol 1995;113:610-614.
ABSTRACT  

Ischemic Macular Edema Recognition and Favorable Natural History in Branch Vein Occlusion
Finkelstein
Arch Ophthalmol 1992;110:1427-1434.
ABSTRACT  

Foveal Avascular Zone Diameter and Sickle Cell Disease
Sanders et al.
Arch Ophthalmol 1991;109:812-815.
ABSTRACT  

Quantification of Diabetic Macular Edema
Smith et al.
Arch Ophthalmol 1987;105:218-222.
ABSTRACT  

Association of Hue Discrimination Loss and Diabetic Retinopathy
Bresnick et al.
Arch Ophthalmol 1985;103:1317-1324.
ABSTRACT