Orbital hypotelorism. An isolated autosomal dominant trait

G. F. Judisch, S. P. Kraft, J. A. Bartley and C. G. Jacoby

Four patients from three consecutive generations of a family with ocular hypotelorism are described. Radiographs document a subnormal distance between the medial orbital walls. To our knowledge, this is the first report of heritable isolated orbital hypotelorism. The pedigree is consistent with an autosomal dominant disorder.