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William J. Durant, MD; Timothy Flood, MD; Morton F. Goldberg, MD; Mark O. M. Tso, MD; Larry A. Pasquali, MD; Gholam A. Peyman, MD

Arch Ophthalmol. 1984;102(6):848-851.

Abstract
• We diagnosed Whipple's disease from the vitreous aspirate of two patients who underwent vitrectomies. In one case, the vitrectomy specimen would have indicated the diagnosis three years before the jejunal biopsy was performed had the appropriate PAS stain been used. In the second case, the PAS-positive macrophages were identified at the time of surgery.

Author Affiliations
From the Departments of Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago (Drs Durant, Flood, Goldberg, Tso, and Peyman) and the University of California, Irvine (Dr Pasquali).

Footnotes
Accepted for publication Feb 13, 1984.

Reprint requests to Department of Ophthalmology, University of Illinois Eye and Ear Infirmary, 1855 W Taylor St, Chicago, IL 60612 (Dr Goldberg).

This study was supported in part by training grant EY7038 and core grant EY1792 from the National Eye Institute, Bethesda, Md, and by an unrestricted research grant from Research to Prevent Blindness, Inc, New York.

Jonas Valatis, MD, provided the biopsy specimens and electron micrographs for case 1, and Maxine Gere gave editorial assistance.

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