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III. Effect of Povidone-Iodine on the Conjunctiva

Leonard Apt, MD; Sherwin Isenberg, MD; Robert Yoshimori, MD; Juan H. Paez, MD

Arch Ophthalmol. 1984;102(5):728-729.

Abstract
• A half-strength povidone-iodine (Betadine) solution was used topically as part of the preoperative chemical preparation of the eye. Aerobic and anaerobic bacterial cultures of the conjunctiva were taken before and after the chemical preparation in 30 consecutive patients; the second eye served as a control. In the control eyes, no significant change in the number of colonies or species of bacteria was found. In the povidone-iodine-treated eyes, the numbers of colonies decreased 91% and the number of species decreased 50% (statistically significant). We therefore recommend that a halfstrength povidone-iodine solution be used as part of the chemical preparation of the eye for surgery.

Author Affiliations
From the Departments of Ophthalmology (Drs Apt, Isenberg, and Paez) and Pathology (Dr Yoshimori), Jules Stein Eye Institute and Harbor-UCLA Medical Center, UCLA School of Medicine.

Footnotes
Accepted for publication Sept 28, 1983.

Reprint requests to Jules Stein Eye Institute, UCLA School of Medicine, Los Angeles, CA 90024 (Dr Apt).

Martin K. Fallor, MD, assisted in obtaining and coding some bacteriologic specimens.

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