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Meimei Chang, MD; Lorenz E. Zimmerman, MD; LTC Ian McLean, MC

Arch Ophthalmol. 1984;102(5):726-727.

Abstract
• We reviewed 6,169 cases in which whole eyes were submitted to the Armed Forces Institute of Pathology (AFIP), Washington, DC, between January 1970 and December 1980. We sought to determine whether there had been any change in the frequency of incorrect diagnoses of malignant melanoma since two previous studies had been conducted at the AFIP. Of 744 eyes with clear media submitted with the clinical diagnosis of malignant melanoma, the rate of incorrect diagnosis was 6.4% (48 of 744 cases). During the 11-year study, the rate of incorrect diagnoses declined from 12.5% to 1.4%. Despite that overall decrease, the locations and frequency of simulating lesions were comparable with those found in the two previous studies. We believe our current findings reflect a significant increase in diagnostic accuracy among clinicians practicing outside of major academic centers.

Author Affiliations
USA

From the Department of Ophthalmology, University of North Carolina, Chapel Hill (Dr Chang), and the Department of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC (Drs Zimmerman and McLean).

Footnotes
Accepted for publication Sept 15, 1983.

Presented in part at the Tenth Annual ( Vitreo-Retinal) Symposium, Washington, DC, April 2, 1982.

The opinions and assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the view of the Department of the Army or the Department of Defense.

Reprint requests to the Department of Ophthalmology, University of North Carolina School of Medicine, 617 Clinical Sciences Bldg, 229H, Chapel Hill, NC 27514 (Dr Chang).

This investigation was supported in part by Research Training Grant EY-07040 from the National Eye Institute, Bethesda, Md, and by a grant from Research to Prevent Blindness, Inc, New York.

Walter D. Foster, PhD, Biometrics Department, AFIP, performed the statistical analysis of our data.

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