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Histopathologic Findings in a Successfully Treated Case

W. Sanderson Grizzard, MD; Elise Torczynski, MD; Devron H. Char, MD

Arch Ophthalmol. 1984;102(4):576-578.

Abstract
• A 47-year-old man with a large (20 x 20 x 12-mm) choroidal melanoma in his only eye was treated with helium ion radiation. The patient retained 6/7.5 visual acuity for 2 years before he was killed in an automobile accident. The eye was ruptured at the time of death; however, histopathologic examination of the eye revealed no residual tumor. The residual ocular mass was composed of eosinophilic amorphous material and macrophages. Necropsy failed to reveal any evidence of metastasis at the time of death. Helium ion charged-particle irradiation in this case was able to completely eradicate the tumor while preserving useful vision.

Author Affiliations
From the Departments of Ophthalmology, University of South Florida College of Medicine, Tampa (Drs Grizzard and Torczynski), and the University of California at San Francisco (Dr Char). Dr Grizzard is now in private practice in Tampa, Fla. Dr Torczynski is now with the Department of Ophthalmology, University of Chicago.

Footnotes
Accepted for publication April 11, 1983.

Reprint requests to 2655 Swann Ave, Suite 100, Tampa, FL 33609 (Dr Grizzard).

This study was supported in part by an unrestricted grant from That Man May See and by grants EY01759, EY01441, and EY03675 and research career development award K04-EY00117 (Dr Char) from the National Eye Institute.

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