Consensual reactions of human blood-aqueous barrier to implant operations
K. Miyake, M. Asakura and K. Maekubo
Slit-lamp fluorophotometry was used to evaluate the disruption of the
blood-aqueous barrier in eyes that underwent posterior chamber lens
implantation following phacoemulsification and the consensual reaction of
the barrier disruption in the contralateral eyes. Topical indomethacin or
placebo was applied to surgically treated eyes to test the effect on the
barrier disruption. Fluorophotometry was carried out before operation and
24 hours, one week, and four weeks after operation. In the surgically
treated eyes, topical indomethacin effectively inhibited the disruption of
the barrier during the first and fourth postoperative weeks; in the
contralateral eyes it did not inhibit the reaction. The consensual reaction
was observed in higher magnitude and frequency than expected. Its magnitude
and frequency were higher during the first postoperative day than during
the first or fourth postoperative weeks, but were proportional to the
barrier disruption of the surgically treated eyes during the first
postoperative day only.
