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Combination Therapy for Dendritic Keratitis High-Titer -Interferon and Trifluridine

Rainer Sundmacher, MD; Kari Cantell, MD; Annegret Mattes

Arch Ophthalmol. 1984;102(4):554-555.

Abstract
• Previous studies showed that the combination of trifluridine with human leukocyte interferon in the treatment of dendritic keratitis is effective, and that the best results were obtained with the highest titer then available (30 x 10⁶ IU/mL). The present study was undertaken to see if an even higher titer (100 x 10⁶ IU/mL) would be more effective. A statistically significant greater effectiveness of the higher titer could not be verified.

Author Affiliations
From the University Eye Clinic, Freiburg, West Germany (Dr Sundmacher and Ms Mattes) and the National Public Health Institute, Helsinki (Dr Cantell).

Footnotes
Accepted for publication March 8, 1983.

Reprint requests to Universitaets-Augenklinik, Killianstrasse 5, D 7800 Freiburg i Br, West Germany (Dr Sundmacher).

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