Static perimetry in chloroquine retinopathy. Perifoveal patterns of visual field depression
W. M. Hart Jr, R. M. Burde, G. P. Johnston and R. C. Drews
Results of threshold static perimetry in nine cases of toxic retinopathy
produced by chloroquine phosphate and hydroxychloroquine sulfate are
reported. Pericentral visual field defects in an advanced case correlated
well with ophthalmoscopically visible defects in the pigment epithelium. In
a less advanced case, perifoveal defects in the visual field of one eye
were found to be demonstrable in the absence of any fundus abnormalities by
either ophthalmoscopy or fluorescein angiography. In both cases, visual
field defects were deepest on the superior or vertical meridian, just above
the point of fixation. Since defects were found to be deepest along the
superior vertical meridian, threshold static perimetry that includes this
location should be the most sensitive method of detecting the early stages
of visual field damage in chloroquine retinopathy.
