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David B. Schaffer, MD; Graham E. Quinn, MD; Lois Johnson, MD

Arch Ophthalmol. 1984;102(3):373-376.

Abstract
• Twenty-six infants with totally resolved low-grade retinopathy of prematurity (ROP) were compared with a similar group of 38 premature infants in whom no retinopathy had ever developed in the nursery. At the examination performed at a physiologic age of 1 year, the two groups were almost indistinguishable with respect to their refractive errors, strabismus, and amblyopia. The incidence and severity of mild to moderate anisometropia was increased in the resolved ROP group. It appears that there is a group of infants in whom absolute resolution occurs, with few residua of active ROP. This is especially true when there are no anatomical retinal findings consistent with low-grade cicatricial retrolental fibroplasia at 1 year of age.

Author Affiliations
From the Division of Ophthalmology, the Children's Hospital of Philadelphia (Drs Schaffer and Quinn); the Departments of Ophthalmology (Drs Schaffer and Quinn) and Pediatrics (Dr Johnson), the University of Pennsylvania School of Medicine; and the Section of Newborn Pediatrics, the Pennsylvania Hospital (Dr Johnson), Philadelphia.

Footnotes
Accepted for publication June 6, 1983.

Read before the 13th meeting of the Jules Gonin Club, Cordoba, Argentina, March 29, 1982.

Reprint requests to Division of Ophthalmology, Children's Hospital of Philadelphia, 1 Children's Center, Philadelphia, PA 19104 (Dr Schaffer).

This study was supported in part by grant RO1 EY 01723 from the National Eye Institute, Bethesda, Md.

Stephen Sinclair, MD, provided assistance in examining the infants' fundi. Rita Divers and Amy Hardin provided secretarial help, and Marion Weston, MS, of the Division of Biostatistics, University of Pennsylvania School of Dental Medicine, Philadelphia, provided statistical analysis.

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