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  Vol. 102 No. 11, November 1984 TABLE OF CONTENTS
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Age-Related Macular Degeneration and Blindness due to Neovascular Maculopathy

Frederick L. Ferris III, MD; Stuart L. Fine, MD; Leslie Hyman, PhD

Arch Ophthalmol. 1984;102(11):1640-1642.


Abstract

• Age-related macular degeneration (AMD) is one of the four most common causes of blindness in the United States. Retinal manifestations of AMD can be categorized as either atrophic or neovascular/exudative. To the best of our knowledge, the proportion of patients legally blind due to the neovascular/exudative manifestations of this disease has not been previously reported. Data from two studies, the Framingham Eye Study and a large case-control study, demonstrate that the vast majority of patients with legal blindness due to AMD have the neovascular/exudative form of the disease. Seventy-nine percent of eyes legally blind due to AMD in the Framingham population and 90% of eyes legally blind due to AMD in the case-control study had neovascular/exudative retinopathy. This is in spite of the fact that neovascular/exudative retinopathy is a relatively infrequent complication of AMD.



Author Affiliations

From the National Eye Institute, National Institutes of Health, Bethesda, Md (Dr Ferris); the Wilmer Institute, The Johns Hopkins Hospital, Baltimore (Dr Fine); and the State University of New York, Stony Brook (Dr Hyman).


Footnotes

Accepted for publication June 4, 1984.

Reprint requests to Bldg 31, Room 6A 24, National Eye Institute, National Institutes of Health, Bethesda, MD 20205 (Dr Ferris).



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