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Conjunctival MyxomaA Clinicopathologic Study of Four Cases and a Review of the Literature
James R. Patrinely, MD;
W. Richard Green, MD
Arch Ophthalmol. 1983;101(9):1416-1420.
Abstract
• Myxomas are benign tumors that resemble a primitive mesenchyma and rarely occur in the conjunctiva. A clinicopathologic study of four new cases is reported, with a review of the clinical, structural, and behavioral characteristics of the previously reported eight cases. In this study, histochemical analysis of the mucous substance indicated that hyaluronic acid and chondroitin sulfates were present. On ultrastructural examination, the myxoma cell had secretory vacuoles and numerous intermediate-sized cytoplasmic filaments. Adults of an average age of 50.8 years were most often affected. The most common initial complaint was of a painless, slow-growing conjunctival mass, present for an average of 31 months. These tumors typically had a smooth, fleshy, gelatinous appearance. The high recurrence rate that has been noted in orbital and cardiac myxomas was not a feature of these conjunctival myxomas. With an average follow-up of 29 months, a single excision appeared to have been adequate treatment.
Author Affiliations
From the Eye Pathology Laboratory, the Wilmer Ophthalmological Institute and Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore.
Footnotes
Accepted for publication Oct 22, 1982.
Read before the 41st Wilmer Residents Association Clinical Meeting, Baltimore, April 23,1982, and the Association for Research in Vision and Ophthalmology, Sarasota, Fla, May 4, 1982.
Reprint requests to the Eye Pathology Laboratory, the Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21205 (Dr Green).
Eva Rostek, RN, translated the Polish material; Irene H. Maumenee, MD, translated the German material; and Elena Barraquer-Somers, MD, translated the French, Spanish, and Italian material.
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