This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (60)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Histopathologic Findings in a Human Eye After 12 Years

Chuo Ni, MD; Wen-Ji Wang, MD; Daniel M. Albert, MD; Charles L. Schepens, MD

Arch Ophthalmol. 1983;101(9):1399-1401.

Abstract
• Histopathologic changes occurred in a human eyeball enucleated 12 years after intravitreous silicone injection for the treatment of complicated retinal detachment with massive preretinal membrane. Silicone "bubbles" (droplets) were found in the chamber angle, iris, ciliary body, retina, and preretinal and subretinal membrane, as well as in the optic nerve. Clinically, glaucoma developed in the eye. A review of the literature indicates that the common late complications of intravitreous silicone injection are cataract, glaucoma, and retinal changes.

Author Affiliations
From the Eye Research Institute of Retina Foundation (Drs Ni, Wang, and Schepens); the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School (Drs Albert and Ni), Boston; and the Eye, Ear, Nose, and Throat Hospital, Shanghai First Medical College (Drs Ni and Wang).

Footnotes
Accepted for publication Feb 14, 1983.

Reprint requests to Library, Eye Research Institute, 20 Staniford St, Boston, MA 02114 (Dr Ni).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Is silicone oil optic neuropathy caused by high intraocular pressure alone? A semi-biological model
Knecht et al.
Br J Ophthalmol 2007;91:1293-1295.
ABSTRACT | FULL TEXT  

Immunopathology of intraocular silicone oil: retina and epiretinal membranes
Wickham et al.
Br J Ophthalmol 2007;91:258-262.
ABSTRACT | FULL TEXT  

Immunopathology of intraocular silicone oil: enucleated eyes
Wickham et al.
Br J Ophthalmol 2007;91:253-257.
ABSTRACT | FULL TEXT  

Visual field defect in association with chiasmal migration of intraocular silicone oil
Eckle et al.
Br J Ophthalmol 2005;89:918-920.
FULL TEXT  

Long term outcome of secondary glaucoma following vitreoretinal surgery
Tranos et al.
Br J Ophthalmol 2004;88:341-343.
ABSTRACT | FULL TEXT  

MR Imaging of Intraventricular Silicone: Case Report
Williams et al.
Radiology 1999;212:151-154.
ABSTRACT | FULL TEXT  

Pseudo-Schnabel's Cavernous Degeneration of the Optic Nerve Secondary to Intraocular Silicone Oil
Shields and Eagle
Arch Ophthalmol 1989;107:714-717.
ABSTRACT  

Effect of Silicone Oil Viscosity on Emulsification
Crisp et al.
Arch Ophthalmol 1987;105:546-550.
ABSTRACT