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Vincent P. deLuise, MD; Khalid F. Tabbara, MD

Arch Ophthalmol. 1983;101(4):634-635.

Abstract
• A simple, rapid, reproducible method of quantifying tear lysozyme levels with a dual-channel spectrophotometer was used to compare normal subjects and those with dry-eye syndrome. The method was sensitive (80%) and specific (85%) and had a predictive value of a positive result of 83%. One patient with clinical manifestations of dry-eye syndrome and paradoxically elevated levels of tear lysozyme was found to have underlying sarcoidosis.

Author Affiliations
From the Francis I. Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California School of Medicine, San Francisco.

Footnotes
Accepted for publication March 23, 1982.

Reprint requests to Francis I. Proctor Foundation, S-315, University of California, San Francisco, CA 94143 (Dr Tabbara).

This study was supported in part by grants EY-03436, EY-01597, and EY-07058 from the National Eye Institute.

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