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James V. Jester, PhD; Richard A. Villasenor, MD; Janet Miyashiro

Arch Ophthalmol. 1983;101(4):611-615.

Abstract
• A 26-year old woman underwent radial keratotomy combined with concentric trephination (6.5 and 8 mm) six months prior to development of multiple epithelial inclusion cysts. A biopsy specimen from one enlarging cyst showed an absence of scarring in addition to the retention of epithelium within a radial incision wound. Adjacent keratocytes were abnormal and seemed to be undergoing degenerative changes. To our knowledge, this is the first report of a failure in corneal wound healing associated with microcystic degeneration of the epithelium following radial keratotomy.

Author Affiliations
From the Estelle Doheny Eye Foundation and the Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles.

Footnotes
Accepted for publication March 24, 1982.

Reprint requests to Estelle Doheny Eye Foundation, 1355 San Pablo St, Los Angeles, CA 90033 (Dr Jester).

This study was supported in part by National Eye Institute grant EY-03562-02 and Core grant EY-03040-03.

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