HLA antigens in Stevens-Johnson syndrome with ocular involvement
B. J. Mondino, S. I. Brown and A. W. Biglan
Fifteen white patients and three black patients with Stevens-Johnson
syndrome (SJS) with ocular involvement had HLA typing performed. The
HLA-Bw44 antigen was found to have an increased frequency of 66.7% in white
patients with SJS with ocular involvement, which was statistically
significant when compared with a frequency of 20.4% in the white control
population. The results of this study suggest that there is an
immunogenetic susceptibility to the development of SJS with ocular
manifestations in white patients.
