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No Discrimination Between Genetic Subtypes

David S. Rothberg, MD; George W. Weinstein, MD; Robert R. Hobson; T. Michael Nork, MD

Arch Ophthalmol. 1982;100(9):1422-1426.

Abstract
• Electroretinography (ERG) has been utilized to claim that the various hereditary subtypes of retinitis pigmentosa (RP) could be distinguished according to the temporal characteristics of the b wave. This study compares two different ERG techniques, one utilizing constant amplitude response and the other balanced photopic and scotopic stimuli, for the early diagnosis of RP. Both methods were found to be reliable objective tests for diagnosing RP. Neither test could differentiate between dominant, autosomal recessive, or X-linked RP.

Author Affiliations
From the Departments of Ophthalmology, University of Kansas, Kansas City (Dr Rothberg); West Virginia University Medical Center, Morgantown (Dr Weinstein and Mr Hobson); and Texas Tech University School of Medicine, Lubbock (Dr Nork).

Footnotes
Accepted for publication Sept 28, 1981.

Reprint requests to Department of Ophthalmology, West Virginia University Medical Center, Morgantown, WV 26506 (Dr Weinstein).

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ABSTRACT