Combined use of neostigmine and ocular motility measurements in the diagnosis of myasthenia gravis

N. R. Miller, J. E. Morris and M. Maquire

Forty-four patients with diplopia caused by myasthenia gravis, ocular myopathies, and ocular motor nerve palsies underwent complete orthoptic evaluations before and after intramuscular injection of neostigmine (Prostigmin) methylsulfate. A test score combining the results of binocular and uniocular measurements was developed that allowed correct correct classification of 70% (31) of patients studied.