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  Vol. 100 No. 3, March 1982 TABLE OF CONTENTS
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Epibulbar IgA Plasmacytoma Occurring in Multiple Myeloma

Rudolph M. Franklin, MD; Kenneth R. Kenyon, MD; W. Richard Green, MD; Rein Saral, MD; Richard Humphrey, MD, PhD

Arch Ophthalmol. 1982;100(3):451-456.


Abstract

• The ophthalmic manifestations of a 51-year-old man with multiple myeloma included exudative retinal detachments and multiple epibulbar plasmacytomas. The retinal changes resolved with treatment for systemic effects, and the IgAproducing plasmacytomas rapidly resolved with local irradiation. The young age of onset (37 years), the prolonged course (14 years), and the IgA M protein and epibulbar involvement were, collectively, unusual findings in multiple myeloma. The presence of epibulbar, gastrointestinal tract, and prostate involvement suggested a homing mechanism of IgAcommitted cells to mucosal surfaces.



Author Affiliations

From the Department of Ophthalmology, Louisiana State University (LSU) Medical Center School of Medicine, New Orleans (Dr Franklin); Department of Ophthalmology, Harvard Medical School, the Cornea Service, Massachusetts Eye & Ear Infirmary, and Department of Cornea Research and Morphology Unit, Eye Research Institute of Retina Foundation, Boston (Dr Kenyon); and Department of Ophthalmology (Dr Green) and the Oncology Unit, Department of Medicine (Drs Saral and Humphrey), The Johns Hopkins University School of Medicine, Baltimore.


Footnotes

Accepted for publication June 29, 1981.

Reprint requests to LSU Eye Center, 136 S Roman St, New Orleans, LA 70112 (Dr Franklin).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

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Arch Ophthalmol 1988;106:524-526.
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