You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


Advertisement

ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | RSS | Access Rights | Sign In


  Vol. 100 No. 11, November 1982 TABLE OF CONTENTS
  Online Only
 •  Online First Table of
Contents
  LABORATORY SCIENCES
 •Online Features
 This Article
 •References
 •Full text PDF
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on Web of Science (6)
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Delicious Add to Digg Add to Facebook Add to Reddit Add to Technorati Add to Twitter What's this?

Importance of Bicarbonate Ion in the Vitreous Space

Akira Negi, MD; Yoshihito Honda, MD; Shin-ichiro Kawano, MD

Arch Ophthalmol. 1982;100(11):1839-1843.


Abstract



• Intraocular irrigating solutions used during vitrectomy must be safe for all tissues surrounding the vitreous space. Bicarbonate and glucose were essential to the maintenance of retinal function. In this study the optimum concentration of bicarbonate in the irrigating solution for the retina was determined electrophysiologically with the use of the in vitro eyecup of the rabbit. In 15 to 25 mmole/L of bicarbonate solutions, the electroretinographic (ERG) b wave was well maintained. Higher concentrations of bicarbonate (35 to 45 mmole/L), which have been considered to be advantageous for the integrity of the corneal endothelium, were shown to suppress the retinal activity. These results were also found in in vivo eyecup, as determined with ERG and visual evoked response. Properly performed open-sky vitrectomy, itself, does not cause severe damage to the normal retinal function.



Author Affiliations



From the Department of Ophthalmology, Kyoto (Japan) University Faculty of Medicine. Dr Negi is now with the Veterans Administration Hospital, Palo Alto, Calif.


Footnotes



Accepted for publication Oct 21, 1981.

Reprint requests to Department of Ophthalmology, VA Hospital, 3801 Miranda Ave, Palo Alto, CA 94304 (Dr Negi).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Delicious Delicious   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | PHYSICIAN JOBS | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1982 American Medical Association. All Rights Reserved.