Talc retinopathy in primates: a model of ischemic retinopathy. III. An electron microscopic study
N. Kaga, M. O. Tso and L. M. Jampol
Electron microscopic study of experimental talc retinopathy provides an
opportunity to study the basic cytologic response of retinal and choroidal
vessels to small, relatively inert emboli. Occlusion of the retinal and
choroidal capillaries resulted primarily from the cellular reaction to,
rather than directly from, the emboli. Mitotic figures in pericytes were
observed. Even though we failed to produce retinal neovascularization (as
is sometimes seen in human talc retinopathy) in this experimental model,
our observations suggest that proliferation of pericytes may be an initial
step in the process of retinal neovascularization.
