Iris nodules in von Recklinghausen's Neurofibromatosis. Electron microscopic confirmation of their melanocytic origin
H. D. Perry and R. L. Font
A 75-year-old man had generalized neurofibromatosis (NFT) with bilateral
iris nodules and a mature cataract with elevated intraocular pressure in
his left eye. At the time of intracapsular cataract extraction, a sector
iridectomy was performed. Electron microscopic studies of the iris nodules
within the iridectomy specimen unequivocally established that the
spindle-shaped cells within the nodules were of melanocytic origin. We
believe that the iris nodules in NFT represent melanocytic hamartomas.
